Thomas E. Ludwig

Publications

On Researchgate

On ORCID

As part of INSERM U1078

  1. R. Bellafqira, T.E. Ludwig, D. Niyitegeka, E. Génin, G. Coatrieux. Privacy-Preserving Genome-Wide Association Study for Rare Mutations – A Secure FrameWork for Externalized Statistical Analysis. IEEE Access, June 2020, doi: 10.1109/ACCESS.2020.3002966. [DOI]
  2. Prof Alexandre Belot, Gillian I Rice, Sulliman Ommar Omarjee, Quentin Rouchon, Eve M D Smith, Marion Moreews, Maud Tusseau, Cécile Frachette, Raphael Bournhonesque, Nicole Thielens, Christine Gaboriaud, Isabelle Rouvet, Emilie Chopin, Akihiro Hoshino, Sylvain Latour, Bruno Ranchin, Rolando Cimaz, Paula Romagnani, Christophe Malcus, Nicole Fabien, Marie-Nathalie Sarda, Behrouz Kassai, Jean-Christophe Lega, Stéphane Decramer, Pauline Abou-Jaoude, Prof Ian N Bruce, Thomas Simonet, Claire Bardel, Pierre Antoine Rollat-Farnier, Sebastien Viel, Héloise Reumaux, James O’Sullivan, Thierry Walzer, Anne-Laure Mathieu, Gaelle Marenne, Thomas Ludwig, Emmanuelle Genin, Jamie Ellingford, Brigitte Bader-Meunier, Tracy A Briggs, Michael W Beresford, Yanick J Crow, FREX Consortium, GENIAL Investigators and the UK JSLE Study Group. Contribution of rare and predicted pathogenic gene variants to childhood-onset lupus: a large, genetic panel analysis of British and French cohorts . The Lancet Rheumatology, January 13, 2020. [DOI]
  3. Ozvan Bocher, Gaëlle Marenne, Aude Saint Pierre, Thomas E. Ludwig, Stéphanie Guey, Elisabeth Tournier-Lasserve, Hervé Perdry, and Emmanuelle Génin. Rare variant association testing for multicategory phenotype. Genetic Epidemiology, May 2019. [DOI]
  4. Tania Cuppens, Thomas E. Ludwig, Pascal Trouvé, and Emmanuelle Genin. GEMPROT: visualization of the impact on the protein of the genetic variants found on each haplotype. Bioinformatics (Oxford, England), December 2018. [ DOI ]
  5. Waqasuddin Khan, Ganapathi Varma Saripella, Thomas Ludwig, Tania Cuppens, Florian Thibord, Emmanuelle Génin, Jean-Francois Deleuze, and David-Alexandre Trégouët. MACARON: a python framework to identify and re-annotate multi-base affected codons in whole genome/exome sequence data. Bioinformatics (Oxford, England), 34(19):3396–3398, October 2018. [ DOI ]
  6. Stéphanie Guey, Markus Kraemer, Dominique Hervé, Thomas Ludwig, Manoëlle Kossorotoff, Françoise Bergametti, Jan Claudius Schwitalla, Simone Choi, Lucile Broseus, Isabelle Callebaut, Emmanuelle Genin, Elisabeth Tournier-Lasserve, and FREX consortium. Rare RNF213 variants in the C-terminal region encompassing the RING-finger domain are associated with moyamoya angiopathy in Caucasians. European journal of human genetics: EJHG, 25(8):995–1003, 2017. [ DOI ]

As part of FrEx Consortium

  1. Prof Alexandre Belot, Gillian I Rice, Sulliman Ommar Omarjee, Quentin Rouchon, Eve M D Smith, Marion Moreews, Maud Tusseau, Cécile Frachette, Raphael Bournhonesque, Nicole Thielens, Christine Gaboriaud, Isabelle Rouvet, Emilie Chopin, Akihiro Hoshino, Sylvain Latour, Bruno Ranchin, Rolando Cimaz, Paula Romagnani, Christophe Malcus, Nicole Fabien, Marie-Nathalie Sarda, Behrouz Kassai, Jean-Christophe Lega, Stéphane Decramer, Pauline Abou-Jaoude, Prof Ian N Bruce, Thomas Simonet, Claire Bardel, Pierre Antoine Rollat-Farnier, Sebastien Viel, Héloise Reumaux, James O’Sullivan, Thierry Walzer, Anne-Laure Mathieu, Gaelle Marenne, Thomas Ludwig, Emmanuelle Genin, Jamie Ellingford, Brigitte Bader-Meunier, Tracy A Briggs, Michael W Beresford, Yanick J Crow, FREX Consortium, GENIAL Investigators and the UK JSLE Study Group. Contribution of rare and predicted pathogenic gene variants to childhood-onset lupus: a large, genetic panel analysis of British and French cohorts . The Lancet Rheumatology, January 13, 2020. [DOI]
  2. Emmanuelle Boscher, Thomas Husson, Olivier Quenez, Annie Laquerrière, Florent Marguet, Kevin Cassinari, David Wallon, Olivier Martinaud, Camille Charbonnier, Gaël Nicolas, Jean-François Deleuze, Anne Boland, Mark Lathrop, Thierry Frébourg, FREX Consortium, Dominique Campion, Sébastien S. Hébert, and Anne Rovelet-Lecrux. Copy Number Variants in miR-138 as a Potential Risk Factor for Early-Onset Alzheimer’s Disease. Journal of Alzheimer’s disease: JAD, 68(3):1243–1255, 2019. [ DOI ]
  3. Thomas Husson, Jean-Baptiste Duboc, Olivier Quenez, Camille Charbonnier, Maud Rotharmel, Macarena Cuenca, Xavier Jegouzo, Anne-Claire Richard, Thierry Frebourg, Jean-François Deleuze, Anne Boland, Emmanuelle Genin, Stéphanie Debette, Christophe Tzourio, Dominique Campion, Gaël Nicolas, Olivier Guillin, and FREX Consortium. Identification of potential genetic risk factors for bipolar disorder by whole-exome sequencing. Translational Psychiatry, 8(1):268, 2018. [ DOI ]
  4. Artem Kim, Clara Savary, Christèle Dubourg, Wilfrid Carré, Charlotte Mouden, Houda Hamdi-Rozé, Hélène Guyodo, Jerome Le Douce, FREX Consortium, GoNL Consortium, Laurent Pasquier, Elisabeth Flori, Marie Gonzales, Claire Bénéteau, Odile Boute, Tania Attié-Bitach, Joelle Roume, Louise Goujon, Linda Akloul, Sylvie Odent, Erwan Watrin, Valérie Dupé, Marie de Tayrac, and Véronique David. Integrated clinical and omics approach to rare diseases: novel genes and oligogenic inheritance in holoprosencephaly. Brain: A Journal of Neurology, 142(1):35–49, 2019. [ DOI ]
  5. Stéphanie Guey, Markus Kraemer, Dominique Hervé, Thomas Ludwig, Manoëlle Kossorotoff, Françoise Bergametti, Jan Claudius Schwitalla, Simone Choi, Lucile Broseus, Isabelle Callebaut, Emmanuelle Genin, Elisabeth Tournier-Lasserve, and FREX consortium. Rare RNF213 variants in the C-terminal region encompassing the RING-finger domain are associated with moyamoya angiopathy in Caucasians. European journal of human genetics: EJHG, 25(8):995–1003, 2017. [ DOI ]
  6. Elodie Persyn, Matilde Karakachoff, Solena Le Scouarnec, Camille Le Clézio, Dominique Campion, French Exome Consortium, Jean-Jacques Schott, Richard Redon, Lise Bellanger, and Christian Dina. DoEstRare: A statistical test to identify local enrichments in rare genomic variants associated with disease. PloS One, 12(7):e0179364, 2017. [ DOI ]
  7. Pierre-Antoine Juge, Raphaël Borie, Caroline Kannengiesser, Steven Gazal, Patrick Revy, Lidwine Wemeau-Stervinou, Marie-Pierre Debray, Sébastien Ottaviani, Sylvain Marchand-Adam, Nadia Nathan, Gabriel Thabut, Christophe Richez, Hilario Nunes, Isabelle Callebaut, Aurélien Justet, Nicolas Leulliot, Amélie Bonnefond, David Salgado, Pascal Richette, Jean-Pierre Desvignes, Huguette Lioté, Philippe Froguel, Yannick Allanore, Olivier Sand, Claire Dromer, René-Marc Flipo, Annick Clément, Christophe Béroud, Jean Sibilia, Baptiste Coustet, Vincent Cottin, Marie-Christophe Boissier, Benoit Wallaert, Thierry Schaeverbeke, Florence Dastot le Moal, Aline Frazier, Christelle Ménard, Martin Soubrier, Nathalie Saidenberg, Dominique Valeyre, Serge Amselem, FREX consortium, Catherine Boileau, Bruno Crestani, and Philippe Dieudé. Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis. The European Respiratory Journal, 49(5), 2017. [ DOI ]
  8. Estelle Colin, Jens Daniel, Alban Ziegler, Jamal Wakim, Aurora Scrivo, Tobias B. Haack, Salim Khiati, Anne-Sophie Denommé, Patrizia Amati-Bonneau, Majida Charif, Vincent Procaccio, Pascal Reynier, Kyrieckos A. Aleck, Lorenzo D. Botto, Claudia Lena Herper, Charlotte Sophia Kaiser, Rima Nabbout, Sylvie N’Guyen, José Antonio Mora-Lorca, Birgit Assmann, Stine Christ, Thomas Meitinger, Tim M. Strom, Holger Prokisch, FREX Consortium, Antonio Miranda-Vizuete, Georg F. Hoffmann, Guy Lenaers, Pascale Bomont, Eva Liebau, and Dominique Bonneau. Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy. American Journal of Human Genetics, 99(3):695–703, 2016. [ DOI ]

As part of CNRS U9002

  1. Fabrice Jossinet, Thomas E Ludwig, and Eric Westhof. RNA structure: bioinformatic analysis. Current Opinion in Microbiology, 10(3):279–285, June 2007. [ DOI ]
  2. Fabrice Jossinet, Thomas E. Ludwig, and Eric Westhof. Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2d and 3d levels. Bioinformatics, 26(16):2057–2059, August 2010. [ DOI ]