Photo professionnelle

Ozvan Bocher

Statistical Genetics | Omics analyses | Human complex traits | QTL

Université de Bretagne Occidentale – UMR1078 GGB

Research

My research areas focus on statistical genetics and omics analyses in the context of human complex traits.
Current projects in the group are detailed hereafter. Please feel free to reach out !

Genetic epidemiology Omics analysis QTL mapping

Projects

GENOMSTAT - Développement de nouvelles méthodes d’analyse de données multi-omiques

My tenure track research project is centered around the development of new multi-omics analyses integrating genetics data.

GOLD-GENOPHENOMET

Description of the salivary microbiome in the French general population and its genetics regulation.

Biomix

Development of multi-omics methods in the tool Biomix

T2DGGI

Member of the T2DGGI Consortium leading large-scale genetic association analyses on Type 2 Diabetes

Open Positions

Staff Scientist Position – GWAS and post-GWAS analyses in the UK Biobank

We are looking for a bioinformatician (18 months contract) to support the team on genetic analyses in the UK Biobank.
Applications are open until June 30th, 2026 and should be sent to ozvan.bocher@univ-brest.fr

📄 Download full position description (PDF)

PhD Position – Multi-omics and applied Mathematics

We are looking for a 3-year PhD candidate to work on the integration of genetic information in multi-omics models.
The position is fully funded and applications are open until April 15th, 2026.

📄 Download full position description (PDF)

Group Members

Member photo
Mohamed Shaaban
PhD Student (2025–2028)
MICROSAL: Investigating the variability of the salivary microbiome and its regulation in the French population

Selected Publications

Bocher O., Arruda A., Yoshiji S., Zhao C., et al. (2026). Unravelling the molecular mechanisms causal to type 2 diabetes across global populations and disease-relevant tissues. Nature Metabolism.

doi:10.1038/s42255-025-01444-1

Rouskas K., Bocher O., et al. (2025). Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health. npj Metabolic Health and Disease.

doi:10.1038/s44324-025-00057-2

Bocher O., et al. (2023). Bridging the diversity gap: Analytical and study design considerations for improving the accuracy of trans-ancestry genetic prediction. HGG Advances.

doi:10.1016/j.xhgg.2023.100214

Bocher O., et al. (2022). Testing for association with rare variants in the coding and non-coding genome: RAVA-FIRST, a new approach based on CADD deleteriousness score. PLoS Genetics.

doi:10.1371/journal.pgen.1009923

Bocher O. and Génin E. (2020). Rare variant association testing in the non-coding genome. Human Genetics.

doi:10.1007/s00439-020-02190-y

Background

2024 – Present

Chaire de Professeur Junior (Tenure track) - UMR1078 – Université de Bretagne Occidentale (Brest)

2022 – 2024

Post-doctoral researcher – ITG - Helmholtz Munich, Germany

2018 – 2021

PhD student in statistical genetics – Université de Bretagne Occidentale

2016 – 2018

Master degree in Public Health, 2nd year in Genetic Epidemiology – Université de Paris Sud

2013 – 2016

Bachelor degree in Biology & Mathematics – Université Paris VI

Contact

Email : ozvan.bocher@univ-brest.fr

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